Di·a·be·tes: a progressive disease where the ability to produce or respond to insulin is impaired, resulting in reduced muscle glycogen, elevated blood sugar, and often hyperinsulinemia.

 

Today’s drugs fail over half of all people with diabetes.

 

We've created a small molecule that can be taken as a pill to lower blood sugar, insulin, and even slow the progression of diabetes.

Insulin Is Not Enough
biOOrg3.14

Insulin Is Not Enough

This discovery will lead to a safe and effective pill to

 

  • Treat People with Rare Disorders Of Insulin Resistance

 

  • Help Women with Polycystic Ovary Syndrome

 

  • Help People with Type-1 Diabetes Manage Insulin & Blood Glucose

  • Prevent People with Type-2 Diabetes From Transitioning to Insulin & Slow or Reverse the Progression of Type-2 Diabetes

About Hyperinsulinemia and the Impacted Conditions
 
Rare Disorders Of Insulin Resistance: include Type B insulin-resistance syndrome, Type A insulin-resistance syndrome, Leprechaunism, Rabson-Mendenhall syndrome, and Lipodystrophies, and are characterized by chronic hyperinsulinemia and its resulting complications.
 
Polycystic Ovary Syndrome: affects about 1 in 5 women, causes unwanted hair growth, acne, weight gain, thinning hair on the scalp, ovarian cysts, irregular periods, and infertility. Most cases of polycystic ovary syndrome are caused by an abnormal response to an increase in testosterone due to chronic hyperinsulinemia.
 
Type-1 Diabetes: About 30% of people with type-one diabetes are insulin resistant. Most people with type-one diabetes are unable to control their blood glucose with insulin alone.

Type-2 Diabetes: Most people with type-two diabetes progress to requiring supplemental insulin. Only about 50% of people with type-two diabetes, who take insulin, are able to control their blood glucose with insulin and current drugs.